These five, plus a cheerful Greek with no English (but a plentiful supply of tequila), head up a jungle trail to find Mathias's brother…the archaeologists…and the ruins.

"The teaser trailer was released on December 2007 and it was attached and shown in front of Among critics who gave the film favorable reviews, [holding his cell phone]  "Director Carter Smith said, "If the audience is going to buy that this vine moves and can get into your body and all that, the world of the film has to be absolutely realistic. There's a testing process you go through with a studio movie and as frustrating as it can be, it also really gives you a good sense of how an audience feels about an ending.

He smears Stacy's blood all over her, then carries her to the bottom of the temple and lays her on the ground. Heinrich left to go see the ruins of the novel’s title and Mathias hasn’t heard from him since. He backs away. [Amy knocks Eric's hat off]

As Mathias' condition worsens, Jeff In the morning Eric brings Amy and Jeff into the tent and tells Stacy to show them what is on her back. Amy gets up and runs through the jungle with the Mayans chasing after her. Jeff and Amy follow with Eric. They befriend a German tourist named Mathias, and a trio of Greeks who go by the Spanish nicknames Pablo, Juan… Mathias : Yeah, some ruins, I think. Four American tourists — Eric, his girlfriend Stacy, her best friend and former roommate Amy, and Amy's boyfriend Jeff, a medical student — are vacationing in Mexico.

As Amy touches one flower, the vines attack and the two barely escape. [after the taxi leaves]  The Ruins. [to Mathias]  After escaping from the Mayans, Amy reaches the Jeep and manages to drive away. As Stacy proceeds to drink, the rest of the group watches her as a vine moves under the skin in her forehead, revealing that her fears are true. Jeff walks over to Stacy trying to calm her down as she has a deep gash on her forehead and is slicing up her thigh to get a vine out. Eric also approaches Stacy, trying to calm her down. While the rest try to restrain Stacy, Eric is dragged away by the vines. Jeff hears moans coming from outside and goes to see what is going on. She turns around and exposes her back and the group can see vines underneath her skin. The vines have also wrapped themselves around Mathias's lower legs and eaten them down to the bone. After Amy's escape, Dimitri's two Greek friends are seen walking through the woods and come up to the temple, looking for him. The group now realizes that the vines are predatory, which is why the Mayans won't let anyone leave. Two young American couples (Jeff and Amy along with Eric and Stacy) vacation in Mexico. Jeff : Kind of like the ones that nobody here wanted to go to, the entire time that we've been here.

The quartet decide to tag along with Mathias in the hope of seeing some real Mayan ruins… The story is based around the discovery of an ancient Mayan Temple. In a small, vine-covered room, the two find the body of the young archaeologist, Heinrich's friend, and a broken phone. As she drives through the jungle, she touches her face and realizes that there are vines growing underneath her skin. Eric pours alcohol over her leg to sterilize it and then cuts it to remove the vine.

The ruins are covered by an unknown plant that isn't as innocent as they appear to be.

Two young couples are on a lazy Mexican vacation–sun-drenched days, drunken nights, making friends with fellow tourists. The Mayans eventually shoot Jeff with arrows. His last known location is an archaeological dig at a remote Mayan ruin in the jungle. As he touches her back to calm her, she spins around and fatally stabs him in the chest. The group reaches the ruins of a Mayan temple, and are confronted by Mayan villagers with guns and bows. He then provokes and berates the Mayans, drawing their attention away from Amy.

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