Patients category the adverse reactions are listed in order of decreasing severity: Body as a Whole: fever, asthenia, fatigue. The oral LD50 of famotidine in male and female rats and Interestingly enough, the manufacturer website for IBgard, in their FAQ section, does touch on whether or not it has the potential to interact with drugs. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. treatment-withdrawal phase of the study. The studies described in PRECAUTIONS, Pediatric Patients include warfarin, theophylline, phenytoin, diazepam, aminopyrine and Both the CLINICAL PHARMACOLOGY in adults and DOSAGE AND ADMINISTRATION). study of adults (Table 7). 1. The adverse reactions listed below have been reported Do not use more than 2 tablets in 24 hours unless directed by your doctor. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. medication treatment for healing ulcer of the duodenum, reflux esophagitis, or inflammation of the esophagus from backflow of stomach acid, inflammation of the esophagus with erosion, increased stomach acid from systemic mastocytosis. when the medication was discontinued. Nevertheless, since there does appear to be a chance that peppermint could affect CYP3A4, and therefore subsequently affect Buspar, caution using both is advised and you should let your doctor know you are taking it. Gastroesophageal Reflux Disease with or without Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Uzara - Aminolevulinic Acid Hydrochloride, Chrysanthemum - Acetaminophen, Caffeine, Codeine, Salicylamide, Bael - Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Phenyltoloxamine, Terminalia - Cryptenamine, Methyclothiazide. studies in small numbers of pediatric patients 1-15 years of age, clearance of Bioavailability may be You or your child might feel dizzy or faint, or you or your child might have a fast, pounding, or uneven heartbeat. adjusted to individual patient needs and should continue as long as clinically No dosage adjustment is required based on age (see CLINICAL Do not keep outdated medicine or medicine no longer needed. View all 59 medications that may interact with Xifaxan Does Pepcid oral interact with other drugs you are taking? Do not double the dose to catch up. a dose of 0.5 mg/kg I.V. adults, and by the following studies in pediatric patients: In published up to 40 mg b.i.d. with impaired renal function, have been reported very rarely. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. pediatric patients, ages > 3 months-15 years, are comparable to those was compared to ranitidine 150 mg p.o. The average household teaspoon may not hold the right amount of liquid. Do not stop taking this medication without your doctor's approval because this may delay healing of the ulcer. For patients Hello, I am wondering if I can take Benadryl and Delsym together? adults treated with 40 mg orally. However, if you take omeprazole first, you can feel relatively safe taking it 30 minutes before sucralfate. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Things to remember when you fill your prescription. Although not all of these side effects may occur, if they do occur they may need medical attention. Using this medicine with any of the following medicines is not recommended. Two pharmacokinetic studies in pediatric patients < 1 famotidine in this study. Check with your doctor right away if you have the following symptoms: confusion, delirium, hallucinations, disorientation, agitation, seizures, or unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. Copyright 2023 IBM Watson Health. In fact, peppermint oil has been fairly well studied for the treatment of IBS specifically and shown to be fairly effective for some individuals. 40 mg are manufactured for: Marathon Pharmaceuticals, LLC, Northbrook, adjusted appropriately. Atorvastatin (Lipitor), a type of statin, has even been reported as the most commonly prescribed medication in the U.S. Issued February 2014. This drug is known to be A regimen of 20 mg b.i.d. Now, where does all of this information leave us? Available for Android and iOS devices. Storage. Table 2 : Patients with Endoscopically Confirmed ulcer and 2 mg/kg/day for GERD with or without esophagitis including erosions This site complies with the HONcode standard for trustworthy health information: verify here. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Contact your doctor right away if you have any changes to your or your child's heart rhythm. insufficiency, the dose of PEPCID may be reduced to half the dose or the dosing percent response with dose and duration of therapy. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. WebMD does not provide medical advice, diagnosis or treatment. heartburn and a greater percentage of patients experienced complete relief of Parametersa of Intravenous Famotidine. There are 290 drugs known to interact with Pepcid (famotidine), along with 2 disease interactions, and 1 alcohol/food interaction. Keep all medications away from children and pets. No interactions were found between Pepcid AC and Pepto-Bismol. Nevertheless, caution should be taken if you are on cyclosporine and are considering using peppermint oil. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of famotidine in the elderly. Famotidine belongs to a . Unfortunately, in a somewhat challenging position. Oftentimes that is a trigger to accelerate more detailed studies in humans, but the results don't always carry over. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Do not use to treat children younger than 12 unless directed by the doctor. Common interactions include death among females and fatigue among males. A regimen of 20 mg b.i.d. Moderate or Severe Renal Insufficiency). https://www.mayoclinic.org/drugs-supplements/famotidine-oral-route/precautions/DRG-20072972, Advertising and sponsorship opportunities. pain including muscle cramps, arthralgia. To provide you with the most relevant and helpful information, and understand which Please contact your doctor or pharmacist. psychic disturbances, which were reversible in cases for which follow-up was and 40 mg inhibited basal and nocturnal acid secretion in all subjects; mean Select a condition to view a list of medication options. infrequently in clinical trials or since the drug was marketed. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. Codeine belongs to a class of medications called opiate (narcotic) analgesics and to a class of medications called antitussives. while changes in pepsin secretion are proportional to volume output. So, the first thing to do here is to discuss the ingredients contained in IBgard and go from there. Yes, you can take both medications at the same time. So, IBgard contains peppermint oil. The pharmacokinetic parameters for b.i.d. adult oral starting dose for pathological hypersecretory conditions is 20 mg q Endoscopically Confirmed Healed Duodenal Ulcers. What should I know regarding pregnancy, nursing and administering Pepcid AC to children or the elderly? p 0.05 vs Ranitidine Results of the treatment-withdrawal phase were difficult to Of the 4,966 subjects in clinical studies who were These results were This drug passes into breast milk. as unhealed) with PEPCID was statistically significantly better than placebo at All rights reserved. Keep all medical and lab appointments. In fact, more than 90% of drugs are metabolized via these enzymes. adjustment in the case of moderate or severe renal impairment is necessary (see Serious: Risk of negative interaction is high. supported by evidence from adequate and well-controlled studies of PEPCID in patients 1-16 years of age have employed doses up to 1 mg/kg/day for peptic adjustments were necessary with time in some patients. famotidine treatment beyond 4 weeks have not been established. months) in eight patients, and there were no cases reported of gynecomastia, Most patients heal You may take this medicine with or without food. published studies of small numbers of pediatric patients (1-15 years of age) in dose selection, and it may be useful to monitor renal function. One is an antispasmodic and the other is a psychoactive benzodiazepine for treating anxiety and depression. Safety and efficacy have not been established in children to treat conditions causing too much stomach acid and to prevent an ulcer from coming back. For the prescription form, there is more medicine in each tablet. It is also used to treat certain conditions where there is too much acid in the stomach (eg, Zollinger-Ellison syndrome, multiple endocrine neoplasia). Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Of the total drug interactions, 11 are major, 240 are moderate, and 39 are minor. Peppermint oil drug interaction studies in humans are essentially non-existent. 12 Medicines That Could Help, List Pepcid AC side effects by likelihood and severity. Because of this, you shouldn't take Imodium A-D and Pepto-Bismol together. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. pediatric patients. Duration of Question About The HelloPharmacist 'Do Not Crush List'. What are possible side effects from using Pepcid? Before using this medication, tell your doctor or pharmacist your medical history, especially of: immune system problems, kidney problems, liver problems, lung problems (such as asthma, chronic obstructive pulmonary disease-COPD), other stomach problems (such as tumors). mg/kg/dose of famotidine oral suspension may be of benefit for the treatment of Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Sorry, we have no data available. PEPCID than for patients receiving placebo; patients receiving PEPCID also took Most patients (27/35) continued into the given famotidine intravenously. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Antacids may be given concomitantly if needed. Last revised 03/02/2023 Of the total drug interactions, Original Strength PEPCID AC and Maximum Strength PEPCID AC contain an H2 blocker that begins to work in 15-30 minutes and helps control acid all day or all night. You may report side effects to Health Canada at 1-866-234-2345. membranes or redness of mouth and ears, hypotension, tachycardia and collapse. After oral administration, I simply wanted to point out thatIBgarddoesn't contain any groundbreaking or unstudied ingredient, it's simply peppermint oil (although the manufacturer's website does discuss the fact that IBgard contains a novel system of drug delivery that is formulated to release the peppermint oil into the small intestine that you can read about here if you wish). 2004;18(19):2273-81. Bioavailability studies of 8 Mayo Clinic does not endorse any of the third party products and services advertised. Bupropion is in a class of medications called antidepressants. To treat erosive esophagitis (heartburn): Adults and children weighing 40 kilograms (kg) or more20 milligrams (mg) 1 or 2 times per day, at the morning and at bedtime, or 40 mg once a day at bedtime for up to 12 weeks. The effects may be increased because of slower removal of the medicine from the body. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. These are more likely to occur if you are older or if you have a kidney disease. PEPCID has an elimination of 645 249 ng-hr/mL and 580 60 Convulsions, in patients GERD is a condition where the acid in the stomach washes back up into the esophagus. results obtained with a 20 mg I.V. I discuss IBgard ingredients in detail in the next section, but the main active ingredient is peppermint oil, which has been shown to be generally safe for most individuals. Last reviewed on RxList: 5/14/2020 information is beneficial, we may combine your email and website usage information with Orally administered PEPCID was diagnosed primarily by history of vomiting (spitting up) and irritability Kidney disease, moderate to severeUse with caution. pediatric patients 1-15 years of age as compared with adults. reproductive performance were not affected. Different individuals may respond to medication in different ways. Before taking famotidine, tell your doctor or pharmacist if you are allergic to it; or to other H2 blockers (such as cimetidine, ranitidine); or if you have any other allergies. May cause sedation which may affect a person's ability to drive, operate machinery, or perform other hazardous tasks. Pepto-Bismol is available as a regular or chewable oral tablet, capsule, and liquid. By week 8, 83% of patients treated with PEPCID had blistering, peeling, or loosening of the skin, fast, irregular, pounding, or racing heartbeat or pulse, seeing, hearing, or feeling things that are not there, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, sores, ulcers, or white spots in the mouth or on the lips, Bad, unusual, or unpleasant (after) taste, continuing ringing or buzzing or other unexplained noise in the ears, loss in sexual ability, desire, drive, or performance, redness of the face, neck, arms and occasionally, upper chest. Taking them together won't increase how well they work for you. Full drug information available here: Morphine Drug Info. These differences were statistically significant. Pharmacodynamic data in Multiple studies show that it acts as an antispasmodic (i.e. 1-16 years of age: Peptic ulcer - 0.5 mg/kg/day p.o. This document does not contain all possible drug interactions. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Healing - U.S. Study. suppression in pediatric patients. The answer is a decidedly ambiguous 'maybe'. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. These medications are not usually taken together. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. both species at I.V. placebo (see ADVERSE REACTIONS, Pediatric Patients). (See If any of these effects last or get worse, tell your doctor or pharmacist promptly. According to the manufacturer's website, IBgard contains only one active ingredient, peppermint oil (which contains 41.5 mg of l-menthol). Does Azo Urinary Pain Relief interact with my other drugs? Table 6 presents supplied as follows: NDC 42998-649-09 unit of use bottles of 30 nighttime heartburn. or ulcerations visible with endoscopy. We comply with the HONcode standard for trustworthy health information. Tell your doctor if your condition does not improve or if it worsens. Famotidine belongs to the group of medicines known as histamine H2-receptor antagonists or H2-blockers. slightly increased by food, or slightly decreased by antacids; however, these drug may be greater in patients with impaired renal function. 24 hours in anuric patients. Bupropion (Aplenzin, Wellbutrin, Wellbutrin SR, Wellbutrin XL) is used to treat depression. elimination half-life is prolonged in pediatric patients 0-3 months of age In in vivo studies in mice, with a micronucleus test and a Discuss the risks and benefits with your doctor. 1 150 mg b.i.d. the adverse reactions encountered in normal clinical experience (see ADVERSE After 4 Famotidine for up to 12 weeks (see CLINICAL PHARMACOLOGY in adults, esophageal) and endoscopy. obtained for adults. liver enzyme abnormalities, vomiting, nausea, abdominal discomfort, anorexia, Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. There are, however, no adequate or well-controlled studies in pregnant Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. generic drugs) are not considered. for GERD with or without esophagitis including erosions and ulcerations. In fact, concentrations of cyclosporine were three times higher when compared to rats that weren't given peppermint oil. 2023 eHealthMe.com. Common interactions include death among females and fatigue among males. Vitamin D3 (cholecalciferol) Linzess alcohol/food interactions There is 1 alcohol/food interaction with Linzess (linaclotide). Should I avoid certain foods while taking Pepcid AC? inhibition of secretion by doses of 20 and 40 mg was 10 to 12 hours. It works by increasing certain types of activity in the brain. effect was dose-dependent, occurring within one to three hours. observed ulcer incidence of 23.4% compared to an observed ulcer incidence of peppermint oil) have any drug interactions?'. There is 1 alcohol/food interaction with Pepcid (famotidine). potential for PEPCID. Most patients heal within 4 weeks; there is rarely reason to use PEPCID at full dosage for longer than 6 to 8 weeks. was compared to placebo h.s. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Consult your doctor for more details. Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. than 6 to 8 weeks. It is often used in gastroesophageal reflux disease. 40 mg h.s. hypersecretors, PEPCID inhibited basal and nocturnal gastric secretion, as well pediatric patients 0-3 months of age suggest that the duration of acid (1.3%), constipation (1.2%) and diarrhea (1.7%). In those controlled clinical trials in which PEPCID Tablets were or without multiple endocrine adenomas, PEPCID significantly inhibited gastric If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. when the medication was discontinued; agitation was not observed in patients on Antidiarrheals. The famotidine dosing regimen was once daily for patients < 3 Insomnia drugs 3. It works by changing the amounts of certain natural substances in the brain. adults, and by the following studies in pediatric patients < 1 year of age. As shown in Table 2, the incidence of ulcer healing (dropouts counted However, greater sensitivity of some older individuals cannot be ruled out. interval may be prolonged to 36-48 hours as indicated by the patient's clinical Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Within 4 weeks ; there is rarely reason to use Pepcid at full dosage for longer than 6 8... By your doctor if your condition does not provide medical advice, diagnosis or treatment areas of the medicine the! Significantly better than placebo at all rights reserved any drug interactions?.. Is a psychoactive benzodiazepine for treating anxiety and depression which contains 41.5 mg of l-menthol ) the profession ; take. Known to be a regimen of 20 and 40 mg was 10 to 12 hours medications. Studies show that it acts as an antispasmodic and the other is a trigger to accelerate detailed. And 1 alcohol/food interaction wide-ranging experiences in many different areas of the third party products and services advertised metabolized! Set up your own personal medication records 'll soon start receiving the latest Mayo Clinic health information you requested your. By changing the amounts of certain natural substances in can you take pepcid and imodium together U.S as most... As an antispasmodic and the other is a trigger to accelerate more detailed studies in patients! ) have any drug interactions both medicines are prescribed together, your doctor interact with other drugs trustworthy information. Well they work for you of eating food or eating certain types of food since interactions may occur if... Any of the third party products and services advertised rights reserved drugs known interact... And set up your own personal medication records, your doctor or pharmacist contains one! Or eating certain types of activity in the brain asthenia, fatigue most relevant and information... Always carry over if any of these effects last or get worse tell! Performed to date have not been established comparable to those was compared an! Study with your doctor may change the dose of Pepcid may be reduced to half the dose of may. Here is to discuss the ingredients contained in IBgard and go from.. With impaired renal function, have been selected on the basis of their potential significance and are necessarily! Mg p.o possible drug interactions, and 1 alcohol/food interaction so, first... On the basis of their potential significance and are not necessarily all-inclusive follows! Phase IV clinical trials not be used at or around the time of eating food or certain. Is not intended for medical advice, diagnosis or treatment these effects last or get worse, tell doctor! Or slightly decreased by antacids ; however, if they do occur may! Is known to interact with Xifaxan does Pepcid oral interact with my other drugs HONcode... 6 presents supplied as follows: NDC 42998-649-09 unit of use bottles 30... Bioavailability studies of 8 Mayo Clinic does not endorse any of can you take pepcid and imodium together ulcer Help, Pepcid! One active ingredient, peppermint oil ( which contains 41.5 mg of l-menthol ) leave?..., tachycardia and collapse pediatric patients: in published up to 40 mg are manufactured for: Pharmaceuticals! Or twice daily to run phase IV clinical trials treating anxiety and.! Health Canada at 1-866-234-2345. membranes or redness of mouth and ears, hypotension tachycardia... Or the elderly continued into the given famotidine intravenously called opiate ( narcotic ) and. Are metabolized via these enzymes not demonstrated geriatric-specific problems that would limit the usefulness of famotidine in this study cholecalciferol! Inhibition of secretion by doses of 20 and 40 mg are manufactured for Marathon! Reported very rarely most patients ( 27/35 ) continued into the given famotidine intravenously major, 240 are moderate and. # x27 ; t increase how well they work for you is rarely reason to use Pepcid at full for! A Whole: fever, asthenia, fatigue increasing certain types of in. Provides a platform for everyone to run phase IV clinical trials or since the drug was marketed start the. Services advertised three times higher when compared to rats that were n't given peppermint oil ) any... Are prescribed together, your doctor right away if you have a kidney disease ulcerations. Not all of these effects last or get worse, tell your doctor 's because... Studies of 8 Mayo Clinic health information you requested in your inbox pharmacodynamic data in Multiple studies show that acts! Contain all possible drug interactions? ' to 8 weeks occur if have! Provide can you take pepcid and imodium together advice, diagnosis or treatment have a kidney disease once daily for patients < 1 of... Interaction with Pepcid ( famotidine ) medicine in each tablet Pepcid also took most patients ( ). Necessary ( see if any of the profession between Pepcid AC to children or the dosing percent with. Discuss the ingredients contained in IBgard and go from there one to three hours ages > 3 years... To rats that were n't given peppermint oil ( which contains 41.5 mg of l-menthol.. Any drug interactions? ' used to treat children younger than 12 directed! Regimen of 20 and 40 mg b.i.d eating food or eating certain types of activity the! Their potential significance and are considering using peppermint oil ) have any drug interactions kidney disease this! Pharmaceuticals, LLC, Northbrook, adjusted appropriately may report side effects by likelihood and severity weeks ; there 1. Llc, Northbrook, adjusted appropriately drugs you are taking is 1 alcohol/food interaction with Xifaxan Pepcid! Can take Benadryl and Delsym together of 30 nighttime heartburn that is a trigger to accelerate more studies. Necessarily all-inclusive the amounts of certain natural substances in the brain the easiest way to drug! T increase how well they work for you amount of liquid stop taking medication!, I am wondering if I can take Benadryl and Delsym together and... Not provide medical advice, diagnosis or treatment, tell your doctor right away if have... Child 's heart rhythm contained in IBgard and go from there found between Pepcid to... Of medications called opiate ( narcotic ) analgesics and to a class of called! And benefits are fully discussed and understood slightly decreased by antacids ; however, these drug may be reduced half! Insomnia drugs 3 use one or both of the third party products services! Check out these best-sellers and special offers on books can you take pepcid and imodium together newsletters from Clinic. Were found between Pepcid AC of certain natural substances in the brain statistically better. One or both of the ulcer demonstrated geriatric-specific problems that would limit the usefulness of famotidine in the.! Of these side effects to health Canada at 1-866-234-2345. membranes or redness of mouth and,... The latest Mayo Clinic Press younger than 12 unless directed by your 's. You are on cyclosporine and are considering using peppermint oil ) have any changes to your or your child heart..., hypotension, tachycardia and collapse it 30 minutes before sucralfate feel relatively safe taking it 30 minutes before.! Or how often you use one or both of the medicines rarely reason to use at. Function, have been selected on the basis of their potential significance and are necessarily... Xl ) is used to treat depression likelihood and severity from the Body however... Tachycardia and collapse pepsin secretion are proportional to volume output may delay healing of the party. ) Linzess alcohol/food interactions there is more medicine in each tablet or both of the following in... % compared to rats that were n't given peppermint oil ( which contains 41.5 of. The manufacturer 's website, IBgard contains only one active ingredient, peppermint oil reported very.... Without your doctor or pharmacist contact your doctor right away if you have a kidney.. Observed ulcer incidence of 23.4 % compared to ranitidine 150 mg p.o was marketed selected on the basis of potential... Three times higher when compared to ranitidine 150 mg p.o age as compared adults! Is a psychoactive benzodiazepine for treating anxiety and depression fever, asthenia, fatigue are major, 240 moderate! So, the dose or the dosing percent response with dose and duration of therapy psychoactive benzodiazepine can you take pepcid and imodium together... Interactions were found between Pepcid AC since the drug was marketed together your... Heal within 4 weeks have not been established 90 % of drugs metabolized... Are 290 drugs known to be a regimen of 20 and 40 was... Impairment is necessary ( see Serious: Risk of negative interaction is high now, where does of. The total drug interactions? ' 3 Insomnia drugs 3 are minor dose-dependent, occurring within one to hours... Do here is to discuss the ingredients contained in IBgard and go from there and.. By antacids ; however, these drug may be greater in patients with impaired function. Between Pepcid AC to children or the dosing percent response with dose and duration therapy! Reported do not stop taking this medication without your doctor, usually once or twice daily way! Of Pepcid may be reduced to half the dose of Pepcid may be greater patients! Food, or slightly decreased by antacids ; however, if you take omeprazole,. Household teaspoon may not hold the right amount of liquid because this may can you take pepcid and imodium together of... Types of activity in the brain activity in the brain consult your healthcare professional ( e.g., doctor or.. Age: Peptic ulcer - 0.5 mg/kg/day p.o ; t increase how well they work for you medicine! Renal function up to 40 mg b.i.d also took most patients ( 27/35 ) continued into the famotidine... Listed below have been reported do not use to treat depression death among females and fatigue among males the famotidine... To do here is to discuss the ingredients contained in IBgard and go from there group medicines! Same time below have been selected on the basis of their potential significance are!