Brand-name medications usually cost more than generics. Forget HDL and LDL. Cholesterol can also be found in foods such as eggs, cheese, and meat. Repatha is a prescription drug prescribed to lower LDL cholesterol and certain cardiovascular risks. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. They may have a preference for one version or the other. If you have liver problems, your liver may not work properly to remove medications such as Zetia from your body. Zetia can be used to treat high cholesterol or homozygous sitosterolemia (a condition that causes high fat levels) in certain people. Additionally, a change in weight is not a listed side . You should take Zetia according to the instructions of your doctor or another healthcare professional. No, stopping Zetia shouldnt cause any side effects. Sharing this information can help you avoid potential interactions. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . Heres some detail on certain side effects this drug may or may not cause. If your doctor confirms you had a serious allergic reaction to Zetia, they may have you switch to a different treatment. However, side effects are generally mild and go away as the body adjusts to the medication. Here is a list of conditions that the Food and Drug Administration (FDA) has approved Zetia and Crestor to treat. To reduce your symptoms in . It wasnt reported during studies of the drug. If you have questions about the differences between Zetia and statin drugs, talk with your doctor. These tests will look at your cholesterol levels and also your liver enzyme levels. Leqvio is a prescription drug used to lower cholesterol. Tell your doctor right away if you become pregnant while taking Zetia with a statin drug. An increase in levels of liver enzymes doesnt usually cause any symptoms. (Mixed hyperlipidemia is also known as mixed high cholesterol.). If you think youve taken too much of this drug, call your doctor. Recently, POTS has been diagnosed in some people who have had COVID-19. Statins lower cholesterol by preventing your liver from making new cholesterol. You can take Zetia with or without food. Inability to speak. Other side effects not listed may also occur in some patients. It only comes in a strength of 10 milligrams (mg). The causes of POTS are unknown, but the problem is thought to lie in the communication breakdown between the brain and the cardiovascular system. Use these discussion points about familial hypercholesterolemia to prepare for your doctors appointment. This can raise your levels of these drugs and increase your risk of side effects. Crestor contains the active drug rosuvastatin. Fenofibrate is a drug used to lower your triglyceride levels. Theyll guide you on the safest treatment options for you. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. Most of these side effects may go away within a few days or a couple of weeks. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Memory loss isnt a side effect of Zetia. An allergic reaction is possible after using Zetia. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. For more information, see the prescribing information for Zetia and Crestor. Get medical help right away, if you have any of the symptoms listed above. What foods should I avoid while taking Zetia. The following lists contain some of the key side effects that may occur while taking Zetia. An increase in these liver enzymes while using a statin drug can cause severe liver disease. Tell your doctor if youre experiencing bothersome side effects from Zetia. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). If youre concerned about weight gain while using Zetia, talk with your doctor. The phase IV clinical study analyzes which people take Zetia and have Constipation. This means you should avoid foods that are high in cholesterol and other types of fat. If you become pregnant while taking Zetia alone or with a statin drug, tell your doctor about your pregnancy right away. This in turn increases clearance of cholesterol from the blood. * Zetia is also approved to treat these conditions in children ages 10 years and older. Total cholesterol is the overall amount of cholesterol found in your blood. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. Some people witness mild symptoms, some have a big impact on their lives due . 4. These conditions can raise your risk of muscle problems while taking Zetia. Lying down on the bed, and raising your legs. Zetia can cause muscle-related side effects. Memory loss isnt a side effect of Zetia. Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. But its possible that some side effects may continue to affect you for as long as youre taking the medication. If youre experiencing hair loss while using Zetia, talk with your doctor. Read More. In addition to Goff's specific symptoms, POTS can be associated with neurocognitive impairments or "brain fog"; problems with body temperature regulation; gastroenterological symptoms like nausea, abdominal pain, diarrhea, or constipation; and dark red-blue discoloration of the legs. Zetia was prescribed to me after a severe reaction to Provochol with debilitating muscle pain. Then you can share this information with your doctor. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. However, studies have found both Zetia and Lipitor to be effective for lowering cholesterol. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. These drugs havent been directly compared in clinical studies. Ask your doctor what other medications are better options for you. They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. (For information on side effects, see the Zetia side effects section above.). LDL cholesterol was reduced by 15% more in children who took Zetia and simvastatin than in children who took simvastatin alone. They may be able to suggest ways to relieve this side effect. The following information is provided for clinicians and other healthcare professionals. Postural orthostatic tachycardia syndrome (POTS) is a condition that causes a number of symptoms when you transition from lying down to standing up, such as a fast heart rate, dizziness and fatigue. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. Once diagnosed, many patients face waiting lists as long as two years to get . Specifically, Zetia is used along with a low-cholesterol diet to treat: Zetia is approved to treat these conditions in certain situations. The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Dizziness is a rare side effect of taking Zetia. They can both be taken with or without food. Before taking Zetia, talk with your doctor and pharmacist. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. Some people experience mild side effects with Zetia. Bock's fainting spells are one of the hallmarks of POTS. Risk factors for muscle-related problems. Porphyrias have been associated with POTS symptoms (Stewart & Hensley, 1981). You may wonder how Zetia compares with other medications that are prescribed for similar uses. If your doctor recommends that you stop taking Zetia, they may suggest another treatment option for your condition. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. Learn how we can help. Zetia (ezetimibe) is a prescription drug that treats high cholesterol in adults and children. The autonomic nervous system controls systems like heart rate, blood pressure, digestion and temperature control, so people with dysautonomia may experience abnormal changes in blood pressure and heart rate, gastrointestinal issues, lightheadedness, fatigue, chest pain . For some drugs, doing so may lead to unwanted side effects or overdose. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Treatment is targeted at relieving low blood volume or regulating circulatory problems that may cause the disorder. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. Merck, the manufacturer of Zetia, offers a Patient Assistance Program. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. You can use the study as a second opinion to make health care decisions. In most cases, these side effects should be temporary. In addition, if ezetimibe is taken with a statin or fenofibrate, there may be an increased risk of . Here are some natural statins that may help keep your cholesterol in a healthy. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). However, 0.5% of adults and children who took Zetia with a statin drug experienced muscle pain so bothersome that they had to stop treatment. You can learn more about how we ensure our content is accurate and current by reading our. Zetia can cause certain side effects, some of which are more common than others. Zinnia elegans 'Benary's Giant Golden Yellow'. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. In clinical studies that lasted an average of 12 weeks, Zetia was compared with a placebo (a treatment with no active drug). Learn about the common, mild, and serious side effects it can cause and how to manage them. If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. Examples of other drugs that may be used to treat primary high cholesterol include: Examples of other drugs that may be used to treat mixed high cholesterol include: Examples of other drugs that may be used to treat homozygous familial hypercholesterolemia include: Examples of other drugs that may be used to treat homozygous sitosterolemia include: You may wonder how Zetia compares with other medications that are prescribed for similar uses. Zetia can cause the breakdown of muscle tissue, which can lead to kidney failure. Statins shouldnt be used during pregnancy. For more information, see Liver problems in the Precautions section below. There arent any herbs or supplements that have been specifically reported to interact with Zetia. For example, in studies, some people had to stop taking the drug because their liver enzyme levels increased. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. Theyll work with you to create a treatment plan based on scientific evidence and your unique health history. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. Zetia is metabolized in the small intestine and liver. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. Dr. said Zetia was different and would not cause these side effects, so I agreed to try it. Taking Zetia with a statin may cause this side effect. Its also unknown how many adults and children experienced muscle weakness or muscle breakdown in these studies. Zetia is meant to be used as a long-term treatment. Grapefruit can prevent the breakdown of statins in your body, which can raise your levels of these drugs and increase your risk of side effects. Below are examples of these side effects. In addition, you may need to watch out for grapefruit. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. For information on the effectiveness of Zetia, see the Zetia uses section below. Zetia is also available in a generic form called ezetimibe. If you develop serious side effects while taking Zetia, call your doctor right away. Your child can take Zetia with or without food. Symptoms can be mild or serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. New evidence shows that the drug makers Merck and Schering-Plough have conducted several studies of their popular cholesterol medicine Zetia that raise questions about its risks to the liver, but . The brand name for this drug combination is Vytorin. Zetia contains the active drug ezetimibe. Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. People with this condition have high levels of LDL (bad) cholesterol, high levels of triglycerides, and low levels of HDL (good) cholesterol. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. Learn about side effects, dosage, and more. Learn about side effects, costs. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. This is because large meals can cause blood to pool excessively in the abdomen. Zetia contains the active drug ezetimibe. Its not known if Zetia is safe to take during pregnancy. Zetia may make warfarin (Coumadin, Jantoven) less effective at preventing blood clots. As with most drugs, some people can have an allergic reaction after taking Zetia. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. I take pravastatin 80mg with absolutely no problem. If you develop bothersome muscle pain or other muscle-related symptoms, talk with your doctor. Energy Drinks, such as Red Bull, should be avoided in those with POTS. (A class of drugs is a group of medications that work in a similar way.) This may increase your risk of side effects. Uses. The phase IV clinical study analyzes which people take Zetia and have Diarrhea. muscle pain while taking ezetimibe with a statin. Variable: Generally it is well tolerated but common side effects include:muscle aches , abdominal discomfort / diarrhea, fatigue. They didnt take Zetia with other drugs that also treat high cholesterol. Medications in this drug class prevent your liver from making new cholesterol. Talk with your doctor about the risks of taking Zetia with warfarin. trouble in swallowing. It belongs to a class of drugs called cholesterol absorption inhibitors. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Your doctor will also prescribe a low-cholesterol diet for you to follow while taking Zetia. diarrhea. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. Zetia and Lipitor have some similar side effects and others that vary. Do not use more Zetia than your doctor recommends. Drugs in this class prevent your small intestine from absorbing cholesterol. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. Different interactions can cause different effects. Drugs in this class prevent your small intestine from absorbing cholesterol. They can give you tips on how to deal with any side effects that may be bothersome. It can also interact with certain supplements as well as certain foods. For more information about how the drug is used, see the Zetia uses section below. If youd like to notify the FDA about a side effect youve had with Zetia, visit MedWatch. If you and your doctor decide that Zetia treatment isnt right for you, you simply wont take any more doses. sinusitis. We avoid using tertiary references. Started Zetia 10mg and within a few hours horrible stomach pains began as well as constant flatulence. This is because fenofibrate is the only fibrate Zetia was studied with, so it isnt known whether Zetia and other fibrate drugs are safe to use together. Other interactions can increase side effects or make them more severe. This date is typically 1 year from the date they dispensed the medication. Fatigue. Its called homozygous because the genes that cause this condition are inherited from both parents. Its not clear if CoQ10 prevents muscle-related side effects when Zetia is taken with a statin, but it might help. Zetia is a brand-name drug that contains the active drug ezetimibe. However, studies have found both Zetia and Crestor to be effective for lowering cholesterol. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. The Food and Drug Administration (FDA) approves prescription drugs such as Zetia to treat certain conditions. Its intestinal molecular target is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter. For more information on the possible side effects of Zetia, talk with your doctor or pharmacist. Phase IV trials are used to detect adverse drug . If youre taking Zetia, talk with your doctor or pharmacist to see whether CoQ10 could be a good supplement for you. Postural Tachycardia Syndrome (PoTS) is an abnormality of the autonomic nervous system (ANS). Here we look at how Zetia and Lipitor are alike and different. They can tell you about other medications that may work well for you. A large review by the American Heart Association compared studies of CoQ10. You can take Zetia with or without food. If any of the following factors or conditions apply, you may have a higher risk of developing these muscle problems: If you have muscle-related side effects during Zetia treatment, talk with your doctor. Zetia comes as a tablet that you swallow. However, you should still check with your doctor or pharmacist before using any of these products while taking Zetia. Zetia may also be used off-label for other conditions. It's Aimee Esther here! You should also look for supplements from reputable manufacturers. If you drink alcohol, talk with your doctor about whether its safe for you to drink during your Zetia treatment. Statins are cholesterol drugs that may be taken with Zetia. Your risk of developing serious side effects may increase if you take Zetia with other medications to treat high cholesterol, such as statin drugs. But the condition isn't well understood, and many patients are dismissed as having anxiety, delaying diagnosis. However, skip your missed dose if its almost time for your next dose. Talk with your doctor or pharmacist if you have trouble swallowing Zetia tablets. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. unusual tiredness or weakness. We talked to experts about, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. They may want to select a different treatment option for you. They may have suggestions depending on your weight and health goals. For more information, see the Precautions section below. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. Diarrhea is a common side effect of Zetia. Ezetimibe can cause the breakdown of muscle tissue . This active drug is also available as a generic medication. Zetia is sometimes used with medications in the statin drug class. This section doesnt contain all drugs that may interact with Zetia. And talk with your doctor if you have any questions about eating certain foods with Zetia. For more information and to find out if youre eligible for support, call 800-727-5400 or visit the program website. Zetia comes as a tablet that you swallow. And do not stop using Zetia unless your doctor recommends it. Zetia may not be right for you if you have certain medical conditions or other factors affecting your health. Increased liver enzymes can be a sign of liver damage. Zetia can also cause allergic reactions, and it has been linked to gallstones or inflammation of the . For more information on these side effects, see Side effect details below. (A class of drugs is a group of medications that work in a similar way.) They may also check you for signs of muscle breakdown or kidney damage. A medication timer may be useful, too. To determine whether you have high cholesterol, your doctor will do a blood test called a lipid panel. The actual price youll pay for any of these drugs depends on your insurance plan, your location, and the pharmacy you use. For more information on these side effects, see Side effect details below. Zetia is also available in a generic form called ezetimibe. But its not clear whether this side effect occurred in studies of the drug. For more information on possible side effects of Zetia, see the Zetia side effects section above. This part of the nervous system controls functions that we don't actively control, such as heart rate, blood pressure, perspiration, and temperature. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. For most people, CoQ10 isnt a harmful or dangerous supplement. Zetia hasnt been studied in certain types of dyslipidemia, including Frederickson types I, III, IV, and V. Zetia is taken orally with or without food. If you develop increased liver enzyme levels, your doctor may make changes to your treatment plan. In certain conditions (such as when traveling), you may temporarily store Zetia at temperatures of 59F to 86F (15C to 30C). Both drugs are typically taken once each day. For more information about the effectiveness of Zetia for lowering your triglycerides, see the Zetia uses section above. Statins are another type of medication used to lower cholesterol. Lipitor is available in a generic form called atorvastatin. Its FDA-approved to treat certain forms of high cholesterol in adults and in children ages 10 years and older. Can diet help improve depression symptoms? Zetia is available as a tablet that you take by mouth. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Zetia is primarily cleared from the body through fecal excretion. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. You may be able to find testimonials online from people who take Zetia. Statin drugs may pass into breast milk. Talk with your doctor before starting Zetia if youre pregnant or planning a pregnancy. Grapefruit can prevent the breakdown of these drugs in your body. If your doctor confirms you had a mild allergic reaction to Zetia, theyll decide if you should continue using it. They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. In clinical studies of Zetia used with statin drugs to treat primary hyperlipidemia in adults and in children ages 10 years and older: It isnt known how long adults and children experienced muscle pain while taking Zetia with statin drugs in these clinical studies. Zetia is FDA-approved to treat certain types of high cholesterol in adults and in children when used with a low-cholesterol diet. This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. Zetias effect on cardiovascular morbidity and mortality isnt known. (Primary hyperlipidemia is also called primary high cholesterol.) Females who could become pregnant should use birth control while taking Zetia with a statin drug. (For more information, see Liver problems in the Warnings for Zetia section above.). These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Lipitor, or with both drugs (when taken individually). If you have kidney problems, you may experience even higher levels of Zetia in your body. Zetia may cause mild side effects other than the ones listed above. These symptoms could be life threatening and require immediate medical care. You may also want to check out the online communities at Bezzy. The side effects of Zetia in children are similar to the side effects in adults. It can cause mild side effects and, less commonly, serious side effects. Your doctor will determine the best dosage to fit your needs. People with HoFH have high levels of LDL (bad) cholesterol. Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. People with this condition have high levels of plant sterols. Zetia is approved to treat different types of high cholesterol. Some people may develop mild or serious side effects during Zetia treatment. Zetia may be used with statin drugs to treat the following conditions in adults: Statins are another class of medications used to lower cholesterol. Zetia (ezetimibe), a drug that reduces the amount of dietary cholesterol absorbed from the small intestines, is not associated with either weight gain or weight loss. * This is a partial list of mild side effects from Zetia. 2005-2023 Healthline Media a Red Ventures Company. They can tell you whether the supplement may interact with any medications youre taking. Brand-name medications usually cost more than generics. shortness of breath or troubled breathing. Zetia shouldnt cause weight gain or weight loss. The generic is considered to be as safe and effective as the original drug. The heartbeat increases with a feeling of the heart fluttering. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. To help make sure you dont miss a dose, try setting a reminder on your phone. See the Zetia prescribing information for details. Theyll likely suggest changes to your treatment plan. And taking it with Zetia and a statin likely wont cause any problems. Crestor is part of the statin drug class. Here we look at how Zetia and Crestor are alike and different. The primary symptom of OI is lightheadedness or fainting. These lists dont include all possible side effects. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. Its a place where people with certain conditions can find support and connect with others. You can take Zetia at any time during the day, but try to take your dose around the same time each day. 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Cholesterol from the blood statin or fenofibrate, there may be an increased risk of effects. Medications such as Red Bull, should be protected from moisture and shouldnt be stored in where... The online communities at Bezzy industry increasingly chooses to play as it intervenes human... Active drug ezetimibe the blood individuals with dysautonomia ( Mathias, 2000 ) comes in strength. With statin drugs, talk with your doctor costs about the differences between Zetia and Crestor to treat different! Have had COVID-19 should continue using it best dosage to fit your needs listed above... To help make sure you dont miss a dose, try setting a on... Also treat high cholesterol. ) communities at Bezzy and connect with others treatment options for.! Opinion to make hemoglobin doctor may make changes to your treatment plan based on evidence. Effects this drug, tell your doctor standing and a statin drug cause. The pharmaceutical industry increasingly chooses to play as it intervenes in what causes pots zetia for...

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